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Correlation between Maternal Zinc Deficiency and Nonsyndromic Cleft Lip with or without Cleft Palate : A Rapid Review


Introduction: Nonsyndromic cleft lip and palate (NS CLP) is a congenital disorder
with the second-highest percentage in Indonesia. One of the ...

  • CodeCallNoLokasiKetersediaan
    Ped1 - 228228 617.64 Mah CJatinangor (Pedodonsia)Tersedia namun tidak untuk dipinjamkan - No Loan
  • Perpustakaan
    Fakultas Kedokteran Gigi
    Judul Seri
    -
    No. Panggil
    617.64 Mah C
    Penerbit FKG Unpad : FKG UNPAD JATINANGOR.,
    Deskripsi Fisik
    -
    Bahasa
    English
    ISBN/ISSN
    160110180156
    Klasifikasi
    617.64
    Tipe Isi
    -
    Tipe Media
    -
    Tipe Pembawa
    -
    Edisi
    -
    Subyek
    Info Detil Spesifik
    -
    Pernyataan Tanggungjawab
  • Introduction: Nonsyndromic cleft lip and palate (NS CLP) is a congenital disorder
    with the second-highest percentage in Indonesia. One of the factors that caused it
    was micronutrient deficiency of the mother. Zinc deficiency during pregnancy is
    suspected can increase the risk of babies with CLP. This rapid review aimed to
    identify the correlation between maternal zinc deficiency and NS CLP. Methods:
    This study was conducted using PRISMA via databases: PubMed, Google Scholar,
    ScienceDirect, ProQuest, and Cochrane Library. All observational design study
    which discusses zinc deficiency and CLP with publication year from 2007 – 2022
    were included. Result: Nine articles were included in this rapid review: eight with
    case-control design and one with cross-sectional design. Samples and methods for
    assessing zinc levels vary in each article. Four articles reported a positive
    correlation between zinc deficiency and CLP while the other five reported no
    correlation. The risk of bias from all articles was low to moderate. Conclusion:
    The included articles showed different findings on the correlation between maternal
    zinc deficiency and NS CLP. A definitive correlation cannot be made due to the
    varied samples and methods, and most articles had a moderate risk of bias.
    Keyword : maternal zinc, zinc deficiency, nonsyndromic clef lip with cleft palate
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