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Drug-like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization
This book explains the drug discovery process and how property based design can increase the success rate of bringing compounds to market. Drug-like ...
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Code CallNo Lokasi Ketersediaan 01021080500225 Tersedia -
Perpustakaan Fakultas FarmasiJudul Seri -No. Panggil 615.1-2 Ker DPenerbit Academic Press : USA., 2008 Deskripsi Fisik Ed.1-Cet.1. xix, 526 hal. Ilus. ; 26,5 cm Index. HBahasa IndonesiaISBN/ISSN 978-0-12-369520-8Klasifikasi 615.1-2 Ker DTipe Isi -Tipe Media -Tipe Pembawa -Edisi NULLSubyek Info Detil Spesifik -Pernyataan Tanggungjawab NULL -
This book explains the drug discovery process and how property based design can increase the success rate of bringing compounds to market. Drug-like properties, such as solubility, permeability, and metabolism, are examined as the fundamental determinants of how drugs behave in vivo. The concepts of pharmacokinetics are discussed with a minimum of mathematical equations, placing emphasis on their practical applications to drug discovery projects. The book has 5 part. Part 1 about introductory concepts. Part 2 about physicochemical properties. Part 2 about physicochemical properties. Part 3 about disposition, metabolism, and safety. Part 4 about methods. Part 5 about specific topics. -
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