Perpustakaan Universitas Padjajaran
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Comparison of Anti-Inflammatory Efficacy Of Curcumin in Curcuma Longa L. with Triamcinolone Acetonide for Minor Recurrent Aphthous Stomatitis: A Systematic Review

Introduction: Recurrent aphthous stomatitis (RAS) is the most common
inflammatory disorder in oral mucous characterized by recurrent ...

  • CodeCallNoLokasiKetersediaan
    IPM1 - 180180 616.31 Pra CJatinangor (Ilmu Penyakit Mulut (OM))Tersedia namun tidak untuk dipinjamkan - No Loan
  • Perpustakaan
    Fakultas Kedokteran Gigi
    Judul Seri
    -
    No. Panggil
    616.31 Pra C
    Penerbit FKG Unpad : FKG UNPAD JATINANGOR.,
    Deskripsi Fisik
    -
    Bahasa
    English
    ISBN/ISSN
    160110180063
    Klasifikasi
    616.31
    Tipe Isi
    -
    Tipe Media
    -
    Tipe Pembawa
    -
    Edisi
    -
    Subyek
    anti-inflammatory
    curcumin
    Curcuma longa
    triamcinolone acetonide
    minor recurrent aphthous stomat
    Info Detil Spesifik
    -
    Pernyataan Tanggungjawab
  • Introduction: Recurrent aphthous stomatitis (RAS) is the most common
    inflammatory disorder in oral mucous characterized by recurrent ulceration. The
    etiology of RAS is multifactorial and still unknown. Thus, the treatment of RAS has
    not been determined. Turmeric (Curcuma longa L.) is a herb known for its
    medicinal properties. It has been used from the ancient times and explored for
    treatment of minor RAS due to its active constituent curcumin (diferuloylmethane).
    Curcumin has various of therapeutic properties, one of them is anti-inflammatory.
    This present study was conducted to evaluate comparison of efficacy of curcumin
    (diferuloylmethane) in Curcuma longa L. with triamcinolone acetonide as antiinflammatory agent for minor recurrent aphthous stomatitis (RAS). Method: The
    search was performed using boolean opeator with keywords ((aphthous stomatitis)
    OR (aphthous ulcers)) AND (curcumin) in six databases, namely PubMed, Scopus,
    EBSCOHost, Cochrane Library, ScienceDirect, and Google Scholar, also adapted
    to the PICO (Population, Intervention, Comparison, Outcome) framework. The
    inclusion criterias for articles were randomized controlled t rial (RCT) study
    design; in the English language; full paper available; published in the range
    between 2011-2021. This study was written by following the Preferred Reporting
    Items for Systematic Review and Meta-analysis (PRISMA) guidelines and the risk
    of bias of the articles was evaluated using RoB-tools JADAD Oxford Quality
    Scoring System. Result: Five articles were included and eligible for analysis. Two
    articles had low risk of bias and three others had high risk of bias. All of articles
    were showed that curcumin is as effective as triamcinolone acetonid required for
    regression in pain and size of the ulcers in minor RAS proved by the measurement
    of pain score was 0 (zero) and ulcer size decreased gradually in both groups in the
    last day of treatment. Conclusion: Curcumin in turmeric (Curcuma longa L.) is as
    effective as triamcinolone acetonide and can be used as an alternative treatment
    modality to topical corticosteroid in the treatment of minor RAS.
    Keywords: curcumin, curcuma longa, triamcinolone acetonide, anti-inflammatory,
    minor recurrent aphthous stomatitis

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