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ANTI-INFLAMMATORY POTENTIAL OF ALOE VERA IN ORAL MUCOSITIS THERAPY: SYSTEMATIC REVIEW


This review aims to analyse the potency of Aloe vera for Oral Mucositis (OM)
therapy. Articles searched using the keywords “Oral ...

  • CodeCallNoLokasiKetersediaan
    IPM1 - 219219 616.31 Cha AJatinangor (Ilmu Penyakit Mulut (OM))Tersedia namun tidak untuk dipinjamkan - No Loan
  • Perpustakaan
    Fakultas Kedokteran Gigi
    Judul Seri
    -
    No. Panggil
    616.31 Cha A
    Penerbit FKG Unpad : FKG UNPAD JATINANGOR.,
    Deskripsi Fisik
    -
    Bahasa
    English
    ISBN/ISSN
    160110180139
    Klasifikasi
    616.31
    Tipe Isi
    -
    Tipe Media
    -
    Tipe Pembawa
    -
    Edisi
    -
    Subyek
    Info Detil Spesifik
    -
    Pernyataan Tanggungjawab
  • This review aims to analyse the potency of Aloe vera for Oral Mucositis (OM)
    therapy. Articles searched using the keywords “Oral Mucositis” AND “Aloe vera”,
    conducted through PubMed, ScienceDirect, and Cochrane Library databases, and
    adapted to the PICO (Population, Intervention, Comparison, Outcome) framework.
    The inclusion criteria for articles were: Randomized Controlled Trial (RCT) study
    design; in English; full paper available; published in the range between 2011-2021;
    and with low risk of bias. RoB-tools JADAD Oxford Quality Scoring System was
    used. This paper writing refers to the Preferred Reporting Items for Systematic
    Review and Meta-analysis (PRISMA) guidelines. A total of 5 (five) articles met the
    criteria for a qualitative review and all showed a high range of quality articles. it
    was found that both Aloe vera solution 70% and Aloe vera gel 10% showed a
    reduction of radiotherapy or chemotherapy induced oral mucositis grade. Aloe vera
    mouthwash has an equal anti inflammation effect compare to benzydamine on
    patient with radiotherapy induced oral mucositis, whereas the use of other formula
    containing Aloe vera with other herbal materials did not show anti-inflammatory
    effect. Drug formulation containing Aloe vera can be used as an alternative therapy
    in the management of Oral Mucositis (OM) with anti-inflammatory potency that
    can reduce pain and the severity of oral mucositis.
    Keywords: Aloe vera, Anti-Inflammation, Oral Mucositis
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