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ANTI-INFLAMMATORY POTENTIAL OF ALOE VERA IN ORAL MUCOSITIS THERAPY: SYSTEMATIC REVIEW
This review aims to analyse the potency of Aloe vera for Oral Mucositis (OM)
therapy. Articles searched using the keywords “Oral ...
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Code CallNo Lokasi Ketersediaan IPM1 - 219 219 616.31 Cha A Jatinangor (Ilmu Penyakit Mulut (OM)) Tersedia namun tidak untuk dipinjamkan - No Loan -
Perpustakaan Fakultas Kedokteran GigiJudul Seri -No. Panggil 616.31 Cha APenerbit FKG Unpad : FKG UNPAD JATINANGOR., 2021 Deskripsi Fisik -Bahasa EnglishISBN/ISSN 160110180139Klasifikasi 616.31Tipe Isi -Tipe Media -Tipe Pembawa -Edisi -Subyek Info Detil Spesifik -Pernyataan Tanggungjawab Verrely Christian Chandra (Author) -
This review aims to analyse the potency of Aloe vera for Oral Mucositis (OM)
therapy. Articles searched using the keywords “Oral Mucositis” AND “Aloe vera”,
conducted through PubMed, ScienceDirect, and Cochrane Library databases, and
adapted to the PICO (Population, Intervention, Comparison, Outcome) framework.
The inclusion criteria for articles were: Randomized Controlled Trial (RCT) study
design; in English; full paper available; published in the range between 2011-2021;
and with low risk of bias. RoB-tools JADAD Oxford Quality Scoring System was
used. This paper writing refers to the Preferred Reporting Items for Systematic
Review and Meta-analysis (PRISMA) guidelines. A total of 5 (five) articles met the
criteria for a qualitative review and all showed a high range of quality articles. it
was found that both Aloe vera solution 70% and Aloe vera gel 10% showed a
reduction of radiotherapy or chemotherapy induced oral mucositis grade. Aloe vera
mouthwash has an equal anti inflammation effect compare to benzydamine on
patient with radiotherapy induced oral mucositis, whereas the use of other formula
containing Aloe vera with other herbal materials did not show anti-inflammatory
effect. Drug formulation containing Aloe vera can be used as an alternative therapy
in the management of Oral Mucositis (OM) with anti-inflammatory potency that
can reduce pain and the severity of oral mucositis.
Keywords: Aloe vera, Anti-Inflammation, Oral Mucositis -
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